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Vol: 60(74) No: 1 / March 2015 Hyperthermic Intraperitoneal Chemotherapy Equipment’s Temperature Control Structure Design using Model Based Techniques Iulia Clitan Department of Automation, Technical University of Cluj-Napoca, Faculty of Automation and Computer Science, 26-28 Baritiu Street, 400127 Cluj-Napoca, Romania, phone: (026) 420-2437, e-mail: iulia.inoan@aut.utcluj.ro Vlad Mureşan Department of Automation, Technical University of Cluj-Napoca, Faculty of Automation and Computer Science, 26-28 Baritiu Street, 400127 Cluj-Napoca, Romania, e-mail: vlad.muresan@aut.utcluj.ro Mihai Abrudean Department of Automation, Technical University of Cluj-Napoca, Faculty of Automation and Computer Science, 26-28 Baritiu Street, 400127 Cluj-Napoca, Romania, e-mail: mihai.abrudean@ aut.utcluj.ro Daniel Moga Department of Automation, Technical University of Cluj-Napoca, Faculty of Automation and Computer Science, 26-28 Baritiu Street, 400127 Cluj-Napoca, Romania, e-mail: daniel.moga@aut.utcluj.ro Corneliu Lungoci Department of Surgery, „Iuliu Hatieganu“ University of Medicine and Pharmacy, 8 Victor Babes Street, 400012, Cluj-Napoca, Romania, e-mail: corneliu.lungoci@umfcluj.ro Keywords: internal model control, hyperthermic intraperitoneal chemotheraphy (HIPEC), model based techniques, model reference control, temperature control structure, peritoneal carcinomatosis. Abstract This paper presents the design of a temperature control structure using model based design techniques. The temperature control structure designed is used in a hyperthermic intraperitoneal chemotherapy (HIPEC) equipment to control the heating process of the cytostatic solution, delivered inside the abdominal cavity. Cytoreductive surgery followed by HIPEC represents the gold standard treatment for peritoneal carcinomatosis, a final stage of abdominal cancer. The HIPEC equipment needs to maintain a homogenous temperature for the cytostatic solution of 42˚C, thus for the design of such a control structure the authors use a Model Reference neural controller and an Internal Model Control controller. Both design techniques use the heating process model to obtain the controller. The designed control structures are compared based on their simulated step responses, since the equipment is in construction phase. References [1] B. Sadeghi, C. Arvieux, O . Glehen, A. C. Beaujard, M. 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